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Showing posts from October, 2014

Twelve Lessons from the AIDS Crisis for Finding an Ebola Treatment

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 There is no perfect solution for Ebola virus disease (EVD). There will be no “cure” for at least some years. Don’t fall into the “If it’s a new disease therefore we need a new drug” trap. We don’t have time for that. It took fifteen years to develop highly effective drugs for HIV. Look for a combination therapy that works – we can’t wait for the perfect “silver bullet” cure. “Don’t let the perfect become the enemy of the good.” Better, more specific anti-Ebola drugs may take years to develop but right now use what we already have that proves effective. Use what works. If there is a credible report of something that actually is effective against Ebola, quickly test that in a simple clinical trial. Once we find two or three medicines that each helps retard Ebola disease or reduces mortality somewhat, then we will have an effective combination therapy. Then keep testing other potential treatments to try to improve that combination. Do not delay simple quick clinical trials. DO THEM N...

Recommended Doses of Selenium for Ebola and HIV

  Recommended Dosages of Selenium for Prophylaxis and Treatment of Ebola Virus Disease and HIV Verified Ebola infected patient:            first day 2400 mcg (12 tablets) 5 tabs – 4 tabs – 3 tabs.             next 8-12 days: 1600-2000 mcg (8-10 tablets) daily until two days after all symptoms stop. Suspected Ebola patient:                         1200mcg (6 tablets x 200mcg Se) per day. 4 tabs – 1 tab -1 tab. If diagnosis is confirmed, then switch to above regimen. If not Ebola infected: continue 3 tablets a day for five days. Health care workers in ETUs, ambulance drivers and burial teams: 3-4   tablets daily based on weight and intensity of contact. Police, checkpoint temperature monitors and emergency service workers: 1-3   tablets daily depending on weight and intensity of c...

Letter to Liberian Ebola Task Force Regarding Truvada

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Dear National Emergency Task Force on Ebola, Again, I write to stress the urgent need to immediately test the HIV drug Truvada against Ebola disease. Truvada is a fifth-generation reverse transcriptase inhibitor drug. It is perhaps ten times as strong against HIV as the lamivudine Dr Gobee Logan claims he had great success with at his ETU in Liberia. Retroviruses like HIV and Ebola require reverse transcriptase to replicate. If you suppress/fully inhibit reverse transcriptase, retroviruses stop multiplying. There is an excellent chance that Truvada will stop Ebola from replicating. However, it is not guaranteed. I guesstimate there is a minimum 50/50 chance this will work against Ebola. If it does work the effect should be extremely strong. If Truvada does work, combined with selenium it should help stop Ebola disease in its tracks. If it works, then anyone who comes to a treatment center during the early symptomatic phase of the disease should live. Those who come too late still may d...